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(2024) demonstrated that compounds such as quercetin, caffeine, and phenethyl ester significantly impaired angiogenic activity by reducing endothelial proliferation and tube formation [65]

Recent studies have also shown that in HIV-positive men on ART, the levels of certain ageing-related cytokines, such as MMP-9, are correlated with persistent HIV-1 infection, suggesting that targeting the ageing pathway may help reduce the viral reservoir [158]

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