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As PatchDock gives an ensemble of possible structures, top 20 docked structures were downloaded and a rigorous selection procedure was followed based on the PatchDock score, ACE values and visualizing the docked structures to select the top hit phytochemicals

(d) Loss of proteostasis involves autophagy and mitophagy, which control organized disposal of cellular debris and are linked to longevity (41)

Reduction of selenium- binding protein 1 sensitizes cancer cells to selenite via elevating extracellular glutathione: A novel mechanism of cancer-specific cytotoxicity of selenite