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Several RNAi drugs, including aptamers like pegaptanib targeting protein targets, and micro interfering RNAs like givosiran and patisiran, as well as antisense oligonucleotides like golodirsen and inotersen that interfere directly with RNA targets, have received FDA approval for medical use (Yu et al., 2020)

One of the most common other nutrients to consider when supplementing the methylation cycle is the proper form of B12. There are 3 different types of B12 that are considered very beneficial to the body (hydroxy B12, methylcobalamin or adenosylcobalamin)

Possible side effects include injection site pain or redness, mild diarrhea, nausea, itching, headache, or dizziness

Check your refrigerator temperature and ensure the vial is not near the freezer compartment or exposed to temperature fluctuations