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Description
Since mitochondrial dysfunction is also involved in the etiology of ME/CFS (525), the literature review also suggested that the anti-fatigue effects of H 2 in animal and human clinical studies indicate a possible ameliorative effect of H 2 on ME/CFS (57, 58, 62, 63)
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A one-electron transfer from NADPH to the complex by cytochrome P-450 reductase to form reduced (Fe ++ ) P-450substrate complex
One of the first chelating agents documented to reduce RS production (specifically the hydroxyl radical) in vitro was diethylenetriaminepentaacetic acid (DTPA)
