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If oral B12 replacement has been trialled in a person with metformin-associated B12 deficiency, I would suggest that a repeat measurement of B12 levels after 812 weeks is a good time to reassess whether absorption is adequate or whether a switch to intramuscular replacement is required
Early identification and treatment of infant B12 deficiency is imperative for their neurological development
By contrast, MIC blends used for weight loss are compounded formulas (ingredients and doses vary by clinic) and are not FDA-approved as weight-loss drugs
In adipose tissue, inhibition of NNMT suppresses de novo lipogenesis, normalizes fat content, and improves insulin sensitivity 2-3
