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This essential vitamin is crucial for brain health, metabolism, and red blood cell production

They work best when combined with a healthy lifestyle

A Cochrane systematic review of NAC for COPD exacerbations (39 RCTs, n=7,436) found that NAC and other mucolytics significantly reduced the frequency of acute exacerbations (OR 0.75, 95% CI 0.62-0.92) (Poole et al., Cochrane Database Syst Rev, 2019) [43]

Yet, GM has been reported to be capable of manipulating vitamin D activity either through upregulating VDR intestinal expression by producing short-chain fatty acid such as butyrate [107], or through competing it for VDR by lithocholic acid, a secondary bile acid [108]