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showed increasing collagen alignment during the initial 17 weeks, but with a simultaneous decrease in collagen 1 staining 41

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One Cochrane review found that high-dose oral vitamin B12 supplements (1,000 mcg to 2,000 mcg per day) was as effective for correcting megaloblastic anemia as B12 shots

However, recently published results from our laboratory detected no evidence of DNA damage or PARP1 activation during M1 macropahge polarization 45
