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Neuropsychopharmacology 42:216241
Hypoxia induces production of L-2-hydroxyglutarate
Nonetheless, the observed effects on essential downstream biomarkers, such as GPX4, ACSL4, and others, support the efficacy and mechanisms of action of these drugs
It undergoes hydrolysis by intracellular esterase, releasing Fluo-4, which binds to calcium with a K d value of 345 nM and emits green fluorescence [45]
