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A peptide that enhances regulatory T cell function, if effective, would theoretically reduce the autoimmune component while preserving or even enhancing the body ability to fight genuine infections

Mice immunization Active immunization experiment was performed with C57BL/6 wild-type mice (6-week-old female mice obtained from Jackson Laboratories, USA)

A dataset of 551,048 particles was subjected to 3D refinements, yielding a final map with a global nominal resolution at 3.1 by the 0.143 criteria of the gold-standard FSC