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AD is the most common type of dementia and can be defined as a slowly progressive neurodegenerative disease characterized by the formation of senile plaques and neurofibrillary tangles via the accumulation of beta-amyloid peptide (A) and tau protein within the most affected brain regions: the medial temporal lobe and neocortical structures [9, 10, 11]

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With the approach of deep learning to discover genes with prognostic value for GBM patients survival, researchers found that NNMT was one of the top ten ranked genes with the highest impact on chemoradiotherapy resistance in GSCs [74]