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Based on this concept, Zhang et al

72 These findings suggest that subnormal ALP levels may be a useful diagnostic tool for HPP, that PLP levels may be useful in patients with a suspected diagnosis of HPP, for screening family members to detect possible heterozygotes, and to monitor response to therapy

10.1039/D2CS00275B 90 JohnstoneT

Improving standards for observational studies can be achieved by registering the study (Choi et al
