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Description
The underlying problem in sickle cell anemia is that the Val for Glu substitution results in hemoglobin tetramers that aggregate into arrays upon deoxygenation in the tissues

At 15 min post-ligation, venograms were taken, captured, and digitized into files on a personal computer and were analyzed using ISSA image software (Vamstec, Zagreb, Croatia)

Set aside the political aesthetics

doi: 10.1073/pnas.0901083106
