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Reduced secretion of gastric acid and pepsin, from the use of H 2 blocker or proton-pump inhibitor (PPI) drugs, can reduce the absorption of protein-bound (dietary) vitamin B 12 , although not of supplemental vitamin B 12

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Key Words: Allodynia, Diclofenac, Rats, Tibial nerve injury, Vitamin B 12 Introduction Neuropathic pain is a consequence of nerve injury characterized by the presence of exaggerated responses to painful stimuli (hyperalgesia), pain response to normally innocuous stimuli (allodynia) and spontaneous pain

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