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Description
For men who do not respond to oral medications, second-line treatments include vacuum erection devices, intracavernosal injections (alprostadil), intraurethral therapy, or penile prosthesis surgery

But they are not a cure

Before pursuing B12 injections or other interventions marketed for weight loss, patients should consult their GP for proper assessment, investigation of any underlying medical conditions affecting weight, and discussion of evidence-based treatment options

Splitting the daily dose into two administrations offers an alternative approach
