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Phase 2b clinical trials conducted on 300 obese test subjects in Australia observed that the peptide appeared to result in consistent weight loss over 12 weeks when introduced once daily

The number of dry licks after the Stimulus in the central port is an indirect measurement of the hedonic value of the tastant

6.2 Antisense Oligonucleotide (ASO) Approaches ASOs targeting NNMT mRNA in liver and adipose tissue have been studied preclinically, showing improvements in insulin sensitivity and reduction of obesity phenotypes without significant toxicity

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