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Some patients with malignant mesothelioma have a deletion on chromosome 1 in the region that encompasses the -GCS gene [40]
Low intracellular zinc induces DNA damage in cells via a combination of increased oxidative DNA damage and disruption of zinc-dependent proteins involved in DNA-repair pathways, leading to impaired DNA repair and altered expression of DNA damage response genes, resulting in DNA strand breaks and genome instability (Ho and Ames, 2002
doi: 10.1080/14397595.2018.1510822 12 JiangSYanWWangSEBaltimoreD
Krishnaswamy G (2021) Critical care management of the patient with anaphylaxis: a Concise definitive review
