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The complete dissolution of the drugs in the volumetric flask was achieved by subjecting it to sonication for a duration of 2 min
132 ZhangW.ContagP
(Japan) 35, 389395 (2014)
As a result, the physiological regulation of Keap1-Nrf2 is lost, and free NAPQI reacts with protein sulfhydryl groups to form APAP adducts (Figure 1)
