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In addition, exogenous IGF-1 administration has been shown to reduce serum glucose levels [95, 143, 144], not only in healthy individuals [140, 145147], but also in those with insulin resistance [148, 149], type I [150152], and T2D [153155]

LOCATION Arequipa is located in the South East of Peru, at an altitude of 2,332 m.a.s.l., Arequipa is bordered on the east by the departments of Puno and Moquegua

2.1.1 Cell surface expression of human CD38 Extracellular CD38 is a type 2 transmembrane molecule, approximately 46 kDa in size, featuring a short cytoplasmic tail that grants high mobility within the liquid bilayer, facilitating the formation of soluble forms of CD38 ( Figure 1 )

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