Peptide Codex
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Description
Time spent at the top and latency to reach the top are zebrafish parameters associated with anxiety-like behaviour (Kysil et al., 2017)
On the molecular level, LDHB silencing induced persistent mitochondrial DNA damage, associated with decreased mitochondrial respiratory complex activity and oxidative phosphorylation, resulting in reduced levels of mitochondria-related metabolites
Metabolism processing of ketone body Fatty acids undergo -oxidation in the mitochondria to form acetyl-CoA (Ac-CoA), which is further metabolized by other enzymes to produce BHB in liver [40, 41]
Arch Toxicol 93 , 33973418 (2019)
