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The specific challenge that was resolved, was the activation of the collateral pathways and upgrading of the particular minor vessel (i.e., remaining episcleral vein that was not cauterized) [11]
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The DiR was also observed in the spinal cord of the mouse further confirming that DiR was delivered to the CNS (central nervous system) [52]

This analysis demonstrated that converting this treatment to oral supplements would save the Ministry of Health and Long-Term Care the costs of the vitamin B12 drug and injections