modifications to glutathione in Skin Aging and Tissue Regeneration: A Systematic Review of Molecular Mechanisms, Redox Modulation, and Biomedical Implications Frontiers | Post-Translational Modification of

Popescu BO, Toescu EC, Popescu LM, Bajenaru O, Muresanu DF, Schultzberg M, Bogdanovic N

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Proteins involved in mitochondrial and cytosolic iron exchange play a crucial role in regulating erastin-induced ferroptosis: CDGSH iron sulfur domain 1 (CISD1, also termed mitoNEET) can inhibit ferroptosis [135], while the BRD7-P53-SLC25A28 axis promotes ferroptosis induction by facilitating mitochondrial iron accumulation and ETC hyperfunction [139]

The infectious agent would trigger a PAIS only when there is an appropriate preexisting individual terrain, which is highly diverse