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These findings provide a foundational epidemiologic context for disease burden and stratification across at-risk groups

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Muscle Aches and Soreness: MSM lowers the expression of COX-2 and iNOS, reducing the localized production of pain-causing prostaglandins in muscle tissues, which is highly beneficial for the widespread myalgia seen in ME/CFS

Table 1 summarizes studies of cell engineering strategies and the corresponding levels of -PL obtained with different -PL producers, and the detailed information is discussed below