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Cardiovascular Diabetology, 23 , 245

94 A meta-analysis that pooled results from five randomized controlled trials found ashwagandha extract improved sleep, increased mental alertness, and decreased anxiety in healthy adults with and without insomnia

It plays a pivotal role in the peripheral conversion of T4 into its active form, T3, via type 1 deiodinase (D1), and also contributes to hormone conjugation, excretion, and the synthesis of key transport proteins such as thyroxine-binding globulin (TBG) and transthyretin

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