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Description
157 ACADSB negatively regulates the expression of GPX4 and glutathione reductase in colon cancer cells, and overexpression of ACADSB increases the concentration of MDA, Fe 2+ and lipid peroxides, inducing cell ferroptosis, and inhibiting the migration and invasion of CRC cells
Furthermore, the same polymorphism was found to be over-represented in patients developing acute liver injury following high doses of paracetamol taken unintentionally over several days [39]
H.CaineE
Levels drop by half by middle age, which impacts the bodys ability to combat age-related conditions and diseases
