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Based on both preclinical and clinical evidence, this review provides an updated overview on the role of folates in restoring transsulfuration balance in HHcy and explores the potential effects of downstream products (such as serine, taurine, and precursors of glutathione) under HHcy conditions

Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes

However, the shorter treatment time for conditioning (typically between 12 weeks before transplant), compared to immunotherapy as a disease treatment, may circumvent these issues that are seen in longer-term treatment strategies

& Sehgal, A