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Its well understood that fasting (to the point of glycogen depletion) triggers gluconeogenesis in the liver (the production of glucose), and cortisol and growth hormone control this process
The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat

But they're generally feeling pretty healthy

Molecular Immunology 92:151160
