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Diverse mechanisms of cisplatin sensitivity/ resistance involve complex processes including drug transport, efflux of drug, detoxification of the drug, response to DNA damage, increased DNA repair, epigenetic changes and autophagy

Vitamin B12 contributes to Energy yielding metabolism Functioning of the nervous system Red blood cell formation Homocysteine metabolism Psychological function Functioning of the immune system Vitamin B12 also plays a role in the process of cell division and the reduction of tiredness and fatigue

[DOI] [PMC free article] [PubMed] [Google Scholar] 381.Shi Y., Liu T., Yao L., Xing Y., Zhao X., Fu J., Xue X

Antioxidant therapies that specifically target mitochondria, such as coenzyme Q10 and mitochondrial-targeted antioxidants (e.g., mitoquinone), have shown promise in reducing mitochondrial oxidative stress and improving sperm motility (93)