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Description
Dysbiotic gut bacteria may trigger syn misfolding and aggregation through inflammatory signals

The involvement of glutamatergic pathways in the pathophysiology of addiction was also confirmed

Astrocytes, positioned at the interface between the brain parenchyma and the perivascular space, which includes capillaries, larger arteries, and veins [66], play a role in the removal of A from the brain via mechanisms that include enzymatic degradation of A and the upregulation of efflux transporters for A at the BBB [67]

doi: 10.1007/s11064-015-1543-z 132 SekarABialasARde RiveraHDavisAHammondTRKamitakiNet al
