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Due to its proximity to the median eminence, ghrelin can easily access the GHSR-expressing cells in the ARC (Schaeffer et al., 2013

213 p62 and dipeptidyl peptidase 9 (DPP9) disrupt the interaction between KEAP1 and NRF2 by competitively binding to KEAP1 to maintain the NRF2 stability and promote the transcription of its downstream iron metabolism and antioxidant genes, resulting in ferroptosis-mediated sorafenib resistance

[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Huang J., Jiang Z., Wang Y., Fan X., Cai J., Yao X., Liu L., Huang J., He J., Xie C
Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload
