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Description
Compared with that in younger mice, the efficacy of the JAK inhibitor ruxolitinib in aged mice is superior, manifesting in the clearance of SnCs, enhancement of physical performance, and maintenance of adipose tissue homeostasis (Table 1)

Lipid-induced lysosomal damage after demyelination corrupts microglia protective function in lysosomal storage disorders

Here are some of the most common causes

doi: 10.1186/s12920-023-01493-2 [DOI] [PMC free article] [PubMed] [Google Scholar] Zaguirre N
