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doi: 10.2478/acph-2019-0003 22 AmeliaB.SaepudinE.CahyanaA

Plant Cell 23 , 24562469 (2011)
The deficiency of catalase in ZZ- A1ATD patients leads to an accumulation of H2O2, which in turn induces increased expression of glutathione peroxidase (GPx)
Further studies are necessary to elucidate the role of AGC1 in cancers such as pancreatic, ovarian, lung, and bone malignancies, particularly regarding its involvement in cancer initiation, progression, and metastasis