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Nanomedicines for the treatment of hematological malignancies
PCM wordt voor 5% onveranderd uitgescheiden via urine en 5-9% wordt geoxideerd door CYP2E1 tot de toxische metaboliet N-acetyl-p-benzoquinone imine (NAPQI)
In a post hoc subgroup analysis by the same group, blinded qualitative scoring of the calluses at 5 weeks suggested that patients who received PTH 134 had a more rich callus formation [33]
