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At the time of the switch, a subset of patients expressed concerns about the long-term impact that it would have on their condition management, and in an online survey many stated that they were dissatisfied with the level of care received

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The eluent was a mixture of methanol and HPLC-grade water with an isocratic ratio of 30:70 [vol/vol] at 1.0 ml/min and 50 C column oven temperature

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