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The spheroids treated with Ru(II)-OH, NP2, or NP4 in a 21% O 2 atmosphere primary consisted of dead cells

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Studies have revealed that one effect of low estrogen concentrations in PMW is GM dysbiosis, which leads to elevated levels of osteoclastogenic cells (Th17 cells, CD4+ T cells) and the pro-osteoclastogenic cytokine TNF-