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Cardiovascular Safety Pramlintide, in addition to insulin, has an effect on weight loss, which is moderate in overweight patients and moderately obese patients and occurs regardless of the reduction of HbA1c

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ArfGAP1 also contains a similar ALPS1 motif (residues 199-234), with both ALPS motifs localized to the non-catalytic C-terminal portion of ArfGAP1 relative to the GAP catalytic domain localized within the first 136 residues [44, 45]

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doi: 10.1016/j.mvr.2024.104683 122

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