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In 2023, the FTC sent warning letters to several branded pharmaceutical companies asserting that patents listed in the Orange Book for drug-device combination products specifically, patents covering the device component rather than the drug itself were improperly listed and that their delisting was warranted [29]

Circular RNA HECTD1 mitigates ulcerative colitis by promoting enterocyte autophagy via miR-182-5p/HuR Axis

NAD, while not a peptide, is frequently administered in the same longevity settings and reflects the broader ecosystem of perioperative supplementation (Gallagher and Emmanuel 2026)