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The kynurenine pathway in schizophrenia and bipolar disorder
Silberfein EJ, Kattepogu KM, Hu CY, Skibber JM, Rodriguez-Bigas MA, Feig B, Das P, Krishnan S, Crane C, Kopetz S , Eng C , Chang GJ
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All these factors disrupt the autophagy machinery, leading to a buildup of protein aggregates and contributing to neuronal toxicity and cell death observed in neurodegenerative conditions ( Nixon et al
