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Indeed, ROS appears to mediate the toxicity of ibuprofen and EtOH as evidenced by increased ROS generation and expression of endogenous antioxidant systems, superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx)

It can, however, complicate other conditions

J Control Release 367:402424 [DOI] [PubMed] [Google Scholar] 28.McCollum L, Karlawish J (2020) Cognitive impairment evaluation and management
