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Disturbed cingulate glutamate metabolism in adults with high-functioning autism spectrum disorder: Evidence in support of the excitatory/inhibitory imbalance hypothesis
[] Studies such as SIGNET (Scottish Intensive care Glutamine or seleNium Evaluative Trial), REDOX (Reducing Deaths due to Oxidative Stress), and MetaPlus reported harmful effects of glutamine supplementation in critically ill patients with organ failure, especially AKI

doi: 10.3390/nu17010067

It works best when combined with adequate dietary fibre (which binds used estrogen in the gut for excretion) and magnesium (which supports Phase II liver detoxification of steroid hormones)
