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Research demonstrates that NNMT expression increases significantly with advancing age, particularly in metabolic tissues, contributing to the progressive decline in NAD+ levels observed during aging

Hepatology 63 , 18601874 (2016)

Acid-reducing medications: Drugs for heartburn or refluxlike Prilosec (omeprazole), Prevacid (lansoprazole), Tagamet (cimetidine), ranitidine, and Zantac 360 (famotidine)lower stomach acid

The pre-authorization request should include the diagnosis code(s), clinical rationale for the imaging guidance, and documentation of any prior conservative treatment trials (physical therapy, oral medications) that failed to provide relief