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Description
How IGF-1 LR3 Works Reduced IGFBP binding The N-terminal extension and R3 substitution disrupt binding to IGF-binding proteins, keeping LR3 free in plasma rather than sequestered
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Results Patient demographics and disease characteristics We recruited 20 male subjects meeting the 2015 ACR/EULAR gout classification criteria, with mean age 60.4 years (11.1) and mean body mass index (BMI) of 31.5 (4.4)
Sample size was chosen empirically based on our previous experience in the calculation of experimental variability
