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Description
During chemotherapy, some nutraceuticals may enhance drug efficacy by inducing cellcycle arrest, differentiation, or altering the redox state of cancer cells

The esr1-1 (enhanced stress response 1) mutant was identified conferring enhanced resistance to the fungal pathogen F

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All TrxR enzymes require an NADPH-dependent reduction step to exert their function in vivo and TrxR is a therapeutic target for cancer and infectious diseases 21,67
