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This explains why topical applications achieve far lower tissue concentrations than injection

Tingling in the hands and feet is another sign of B12 deficiency

Symptoms of B12 Deficiency The symptoms of vitamin B12 deficiency include a mixture of the physical symptoms associated with peripheral neuropathy, as well as cognitive issues: Physical Symptoms Peripheral Neuropathy experiencing unpleasant sensations in the extremities (the hands, arms, legs and feet) due to nerve damage, such as those listed above Despite feeling the minor irritating phenomenon of pins and needles, persistently feeling the sensation may suggest that you have nerve damage, which should be taken seriously Issues with your eyesight, such as visual disturbances or impairments Experiencing paralysis in areas such as the extremities can suggest that nerve damage has become severe, so medical intervention should be sought as soon as possible

A consultation with a qualified healthcare provider is essential to evaluate individual health status and determine if this treatment is appropriate