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Description
It has been patented for potential use in neurodegenerative conditions, but clinical drug approval processes are ongoing

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Owing to the pronounced mutagenicity and the carcinogenic potential of many NAs, NA impurities in pharmaceuticals are designated as a "cohort of concern" under the ICH M7(R2) guideline, for which the corresponding Threshold of Toxicological Concern (TTC) approach is not considered appropriate (European Medicines Agency 2025)

Bell, MD, FACP By Jon Johnson on July 20, 2020, viewed on December 28, 2022
