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As consumer awareness of the skin barrier has grown dramatically in recent years, products designed to support barrier stability have become extremely popular
doi: 10.1111/j.1471-4159.2006.03907.x 115
As mentioned, GSH can be oxidized to GSSG under oxidative stress and then rapidly converted back to GSH with glutathione reductase (GR) as the catalysis
Similar metabolic plasticity has been documented in breast cancer models, where basal-like breast CSCs frequently exhibit a heightened glycolytic phenotype, as evidenced by elevated expression of enzymes such as hexokinase 2 and lactate dehydrogenase A
