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Description
Glioma-associated microglia and infiltrating macrophages (GAMs), which constitute a significant portion of the tumor mass, are critical targets for immunotherapy [65,66]
Moreover, FeS cluster assembly and disassembly in mammalian iron regulatory protein-1 (IRP1) alters the active site conformation and accessibility and determines whether IRP1 binds its mRNA targets in response to oxidative stress and intracellular iron levels (reviewed in Refs
Gieling ET, Schuurman T, Nordquist RE, van der Staay FJ
10.3233/JAD-170050 J
