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Activated Nrf2 promotes the gene expression of several antioxidant enzymes and proteins, such as superoxide dismutase (SOD), glutathione S-transferase (GST), glutathione peroxidase (GPx), heme oxygenase-1 (HO-1), and NAD(P)H as a means of protecting the cells from oxidative stress and maintaining the dynamic balance between oxidation and antioxidant protection

circles indicate individual samples of astrocytes from different groups

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