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Calcitonin 100 ng l 1 as measured by the central laboratory at screening
A 2025 European Journal of Clinical Nutrition commentary on the NICE guideline argued that the diagnostic threshold and clinical awareness still need to be tightened further, especially around pernicious anaemia, which is still under-recognised in primary care
Neurological symptoms can include tingling or numbness in the hands and feet (peripheral neuropathy), a sensation often described as "pins and needles"
