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& Grandillo S

10.1016/j.inoche.2024.113004 197 SubramaniamP.NishaK

Through a compound screen targeting ZnT8-mediated zinc transport, we identified anisomycin (ANS), a multifunctional drug (Fig

Addition of GGCT inhibition specifically targets the intrinsic mechanisms that enable glioblastoma cells to resist xCT inhibition, thereby providing a novel therapeutic strategy to efficiently induce ferroptosis in this highly aggressive and devastating malignancy