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Description
The evidence is clear: NNMT activity, NAD+ synthesis, and sirtuin responsiveness are all circadian-regulated, and administering the compound outside the optimal metabolic window cuts efficacy by 3050%
sinensis showed the presence of ferulic acid (13) and Butylphthalide (14), which are known for their effect on serotonergic and dopaminergic systems [50] and the ability to protect against neuronal damage [51, 52]

2010;8(9):e1000479

Other effective ingredients include arbutin, kojic acid, tranexamic acid, vitamin C, and retinoids, which help reduce pigmentation and promote skin renewal
